Form FWP MORGAN STANLEY Filed by: MORGAN STANLEY

Stahlman

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October
2020

Preliminary
Terms No. 4,962

 Registration
Statement Nos. 333-221595; 333-221595-01

Dated
September 25, 2020

 Filed
pursuant to Rule 433

 

Morgan
Stanley Finance LLC

Structured Investments

Opportunities in Commodities

Buffered PLUS Based on the iShares®
Silver Trust due October 5, 2023

Buffered Performance Leveraged Upside SecuritiesSM

Fully and Unconditionally Guaranteed by Morgan Stanley

Principal at Risk
Securities

The Buffered PLUS offered are unsecured
obligations of Morgan Stanley Finance LLC (“MSFL”) and are fully and unconditionally guaranteed by Morgan Stanley.
The Buffered PLUS will pay no interest, provide a minimum payment at maturity of only 15% of the stated principal amount and have
the terms described in the accompanying prospectus supplement and prospectus, as supplemented or modified by this document. At
maturity, if the underlying commodity shares have appreciated in value, investors will receive the stated principal amount of
their investment plus leveraged upside performance of the underlying commodity shares, subject to the maximum payment at maturity.
If the underlying commodity shares have depreciated in value, but the underlying commodity shares have not declined by more than
the specified buffer amount, the Buffered PLUS will redeem for par. However, if the underlying commodity shares have declined
by more than the buffer amount, investors will lose 1% for every 1% decline beyond the specified buffer amount, subject to the
minimum payment at maturity of 15% of the stated principal amount. Investors may lose up to 85% of the stated principal amount
of the Buffered PLUS.
The Buffered PLUS are for investors who seek a commodity-based return and who are willing to risk their
principal and forgo current income and upside above the maximum payment at maturity in exchange for the leverage and buffer features
that in each case apply to a limited range of performance of the underlying commodity shares. The Buffered PLUS are notes issued
as part of MSFL’s Series A Global Medium-Term Notes program.

All payments are subject to
our credit risk. If we default on our obligations, you could lose some or all of your investment. These Buffered PLUS are not
secured obligations and you will not have any security interest in, or otherwise have any access to, any underlying reference
asset or assets.

SUMMARY TERMS
Issuer: Morgan Stanley Finance LLC
Guarantor: Morgan Stanley
Maturity date: October 5, 2023
Underlying commodity
shares:
Shares of the iShares® Silver Trust
Aggregate principal
amount:
$
Payment at maturity
per Buffered PLUS:

§  If
the final share price is greater than the initial share price:
$10 + leveraged upside payment

In
no event will the payment at maturity exceed the maximum payment at maturity.

  §
    If the final share price is less than or equal to the initial share price but has decreased from the initial share
price by an amount less than or equal to the buffer amount of 15%: $10
  §  If
the final share price is less than the initial share price and has decreased from the initial share price by an amount
greater than the buffer amount of 15%:
         ($10
x the share performance factor) + $1.50
 

Under these
circumstances, the payment at maturity will be less than the stated principal amount of $10.

However,
under no circumstances will the Buffered PLUS pay less than $1.50 per Buffered PLUS at maturity.
 

Leveraged upside payment: $10 x leverage factor x share percent increase
Share percent increase: (final share price – initial share price)
/ initial share price
Share performance factor: final share price / initial share price
Initial share price:
$       , which
is the closing price of one underlying share on the pricing date
Final share price:
The closing price of one underlying share on the
valuation date times the adjustment factor on such date
Adjustment factor: 1.0, subject to adjustment in the event of certain
events affecting the underlying commodity shares
Valuation date: October 2, 2023, subject to postponement for non-trading
days and certain market disruption events
Leverage factor: 300%
Buffer amount: 15%.  As a result of the buffer amount
of 15%, the value at or above which the underlying commodity shares must close on the valuation date so that investors do
not suffer a loss on their initial investment in the Buffered PLUS is $         ,
which is 85% of the initial share price.
Minimum payment at
maturity:
$1.50 per Buffered PLUS (15% of the stated principal
amount)
Maximum
payment at maturity:
$15.20 per Buffered PLUS (152.00% of the stated
principal amount)
Interest: None
Stated principal amount: $10 per Buffered PLUS
Issue price: $10 per Buffered PLUS
Pricing date: October 2, 2020
Original issue date:
October 7, 2020 (3 business days after the pricing
date)
CUSIP: 61771D555
ISIN: US61771D5555
Listing: The Buffered PLUS will not be listed on any securities
exchange.
Agent: Morgan Stanley & Co. LLC (“MS &
Co.”), an affiliate of MSFL and a wholly owned subsidiary of Morgan Stanley.  See “Supplemental information
regarding plan of distribution; conflicts of interest.”
Estimated value on the pricing date: Approximately $9.061 per Buffered PLUS, or within
$0.45 of that estimate.  See “Investment Summary” on page 2.
Commissions
and issue price:
Price
to public
Agent’s
commissions and fees
Proceeds
to us(3)
Per Buffered PLUS $10 $0.25(1)  
    $0.05(2) $9.70
Total $ $ $
(1) Selected dealers, including
Morgan Stanley Wealth Management (an affiliate of the agent), and their financial advisors will collectively receive from the
agent, MS & Co., a fixed sales commission of $0.25 for each Buffered PLUS they sell. See “Supplemental information regarding
plan of distribution; conflicts of interest.” For additional information, see “Plan of Distribution (Conflicts of
Interest)” in the accompanying prospectus supplement for PLUS.
(2) Reflects a structuring fee
payable to Morgan Stanley Wealth Management by the agent or its affiliates of $0.05 for each Buffered PLUS.
(3) See “Use of proceeds
and hedging” on page 19.

The
Buffered PLUS involve risks not associated with an investment in ordinary debt securities. See “Risk Factors” beginning
on page 6.

The Securities
and Exchange Commission and state securities regulators have not approved or disapproved these securities, or determined if this
document or the accompanying prospectus supplement and prospectus is truthful or complete. Any representation to the contrary
is a criminal offense.
 

The Buffered
PLUS are not deposits or savings accounts and are not insured by the Federal Deposit Insurance Corporation or any other governmental
agency or instrumentality, nor are they obligations of, or guaranteed by, a bank.

You should
read this document together with the related prospectus supplement and prospectus, each of which can be accessed via the hyperlinks
below. Please also see “Additional Terms of the Buffered PLUS” and “Additional Information About the Buffered
PLUS” at the end of this document.

As used in
this document, “we,” “us” and “our” refer to Morgan Stanley or MSFL, or Morgan Stanley and
MSFL collectively, as the context requires.
 

Prospectus Supplement for PLUS dated November 16, 2017      Prospectus dated November 16, 2017

 

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

Investment Summary

Buffered Performance Leveraged Upside Securities

Principal
at Risk Securities

 

The Buffered PLUS Based on the iShares® Silver
Trust due October 5, 2023 (the “Buffered PLUS”) can be used:

 

§ As an alternative to direct exposure to the underlying commodity shares that enhances returns
for a certain range of positive performance of the underlying commodity shares, subject to the maximum payment at maturity

 

§ To enhance returns and potentially outperform the underlying commodity shares in a moderately
bullish scenario

 

§ To achieve similar levels of upside exposure to the underlying commodity shares as a direct investment,
subject to the maximum payment at maturity, while using fewer dollars by taking advantage of the leverage factor

 

§ To obtain a buffer against a specified level of negative performance in the underlying commodity
shares

 

Maturity: Approximately 3 years
Leverage
factor:
300%
Maximum
payment at maturity:
$15.20 per Buffered PLUS (152.00% of the stated principal amount)
Minimum
payment at maturity:
$1.50 per Buffered PLUS (15% of the stated principal amount).  Investors may lose up to 85% of the stated principal amount of the Buffered PLUS.
Buffer
amount:
15%
Coupon: None

 

The original issue price of each Buffered PLUS is $10. This price
includes costs associated with issuing, selling, structuring and hedging the Buffered PLUS, which are borne by you, and, consequently,
the estimated value of the Buffered PLUS on the pricing date will be less than $10. We estimate that the value of each Buffered
PLUS on the pricing date will be approximately $9.061, or within $0.45 of that estimate. Our estimate of the value of the Buffered
PLUS as determined on the pricing date will be set forth in the final pricing supplement.

 

What goes into the estimated value on the pricing date?

 

In valuing the Buffered PLUS on the pricing date, we take into
account that the Buffered PLUS comprise both a debt component and a performance-based component linked to the underlying commodity
shares. The estimated value of the Buffered PLUS is determined using our own pricing and valuation models, market inputs and assumptions
relating to the underlying commodity shares, instruments based on the underlying commodity shares, volatility and other factors
including current and expected interest rates, as well as an interest rate related to our secondary market credit spread, which
is the implied interest rate at which our conventional fixed rate debt trades in the secondary market.

 

What determines the economic terms of the Buffered PLUS?

 

In determining the economic terms of the Buffered PLUS, including
the leverage factor, the maximum payment at maturity, the buffer amount and the minimum payment at maturity, we use an internal
funding rate, which is likely to be lower than our secondary market credit spreads and therefore advantageous to us. If the issuing,
selling, structuring and hedging costs borne by you were lower or if the internal funding rate were higher, one or more of the
economic terms of the Buffered PLUS would be more favorable to you.

 

What is the relationship between the estimated value on the
pricing date and the secondary market price of the Buffered PLUS?

 

The price at which MS & Co. purchases the Buffered PLUS in
the secondary market, absent changes in market conditions, including those related to the underlying commodity shares, may vary
from, and be lower than, the estimated value on the pricing date, because the secondary market price takes into account our secondary
market credit spread as well as the bid-offer spread that MS & Co. would charge in a secondary market transaction of this type
and other factors. However, because the costs associated with issuing, selling, structuring and hedging the Buffered PLUS are not
fully deducted upon issuance, for a period of up to 6 months following the issue date, to the extent that MS & Co. may buy
or sell the Buffered PLUS in the secondary market, absent changes in market conditions, including those related to the underlying
commodity shares, and to our secondary market credit spreads, it would do so based on values higher than the estimated value. We
expect that those higher values will also be reflected in your brokerage account statements.

 

MS & Co. may, but is not obligated to, make a market in the
Buffered PLUS, and, if it once chooses to make a market, may cease doing so at any time.

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

Key Investment Rationale

 

The Buffered PLUS offer leveraged upside exposure to the underlying
commodity shares, subject to the maximum payment at maturity, while providing limited protection against negative performance of
the underlying commodity shares. Once the underlying commodity shares have decreased in price by more than a specified buffer amount,
investors are exposed to the negative performance of the underlying commodity shares, subject to the minimum payment at maturity.
At maturity, if the underlying commodity shares have appreciated, investors will receive the stated principal amount of their investment
plus leveraged upside performance of the underlying commodity shares, subject to the maximum payment at maturity. At maturity,
if the underlying commodity shares have depreciated and (i) if the closing price of the underlying commodity shares has not declined
from the initial share price by more than the specified buffer amount, the Buffered PLUS will redeem for par, or (ii) if the closing
price of the underlying commodity shares has declined by more than the buffer amount, the investor will lose 1% for every 1% decline
beyond the specified buffer amount, subject to the minimum payment at maturity. Investors may lose up to 85% of the stated principal
amount of the Buffered PLUS.

 

Leveraged
Performance up to a Cap

The Buffered PLUS offer investors an opportunity to capture enhanced returns for a certain range of positive performance relative to a direct investment in the underlying commodity shares, subject to the maximum payment at maturity.

 

Upside
Scenario

The underlying commodity shares increase in price, and, at maturity, the Buffered PLUS redeem for the stated principal amount of $10 plus 300% of the share return, subject to the maximum payment at maturity of $15.20 per Buffered PLUS (152.00% of the stated principal amount).

 

Par
Scenario

The underlying commodity shares decline in price by no more than 15%, and, at maturity, the Buffered PLUS redeem for the stated principal amount of $10.

 

Downside
Scenario
The underlying commodity shares decline in price by more than 15%, and, at maturity, the Buffered PLUS redeem for less than the stated principal amount by an amount that is proportionate to the percentage decrease of the underlying commodity shares from the initial share price, plus the buffer amount of 15%.  (Example: if the underlying commodity shares decrease in price by 35%, investors would lose 20% of their principal and the Buffered PLUS will redeem for $8.00, or 80% of the stated principal amount.)  The minimum payment at maturity is $1.50 per Buffered PLUS.

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

How the Buffered PLUS Work

 

Payoff Diagram

 

The payoff diagram below illustrates the payment at maturity
on the Buffered PLUS based on the following terms:

 

Stated
principal amount:
$10 per Buffered PLUS
Leverage factor: 300%
Buffer amount: 15%
Maximum payment
at maturity:
$15.20 per Buffered PLUS
Minimum payment
at maturity:
$1.50 per Buffered PLUS

 

Buffered PLUS Payoff Diagram

 

How it works

 

§ Upside Scenario. If the final share
price is greater than the initial share price, investors will receive the $10 stated principal amount plus 300% of the appreciation
of the underlying commodity shares over the term of the Buffered PLUS, subject to the maximum payment at maturity. An investor
will realize the maximum payment at maturity of $15.20 per Buffered PLUS at a final share price of approximately 117.333% of the
initial share price.

 

§ If the value of the underlying commodity shares appreciate 2%, the investor would receive a 6%
return, or $10.60 per Buffered PLUS.

 

§ If the value of the underlying commodity shares appreciate 60%, the investor would receive only
the maximum payment at maturity of $15.20 per Buffered PLUS, or 152.00% of the stated principal amount.

 

§ Par Scenario. If the final share
price is less than or equal to the initial share price but has decreased from the initial share price by an amount less than or
equal to the buffer amount of 15%, investors will receive the stated principal amount of $10 per Buffered PLUS.

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

§ Downside Scenario. If the final share
price is less than the initial share price and has decreased from the initial share price by an amount greater than the buffer
amount of 15%, investors will receive an amount that is less than the stated principal amount by an amount that is proportionate
to the percentage decrease in the value of the underlying commodity shares from the initial share price, plus the buffer amount
of 15%. The minimum payment at maturity is $1.50 per Buffered PLUS.

 

§ For example, if the value of the underlying commodity shares depreciate 50%, investors would
lose 35% of their principal and receive only $6.50 per Buffered PLUS at maturity, or 65% of the stated principal amount.

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

Risk Factors

 

The following is a non-exhaustive list of certain key risk
factors for investors in the Buffered PLUS. For further discussion of these and other risks, you should read the section entitled
“Risk Factors” in the accompanying prospectus supplement for PLUS and prospectus. You should also consult with your
investment, legal, tax, accounting and other advisers in connection with your investment in the Buffered PLUS.

 

§ Buffered PLUS do not pay interest and provide a minimum payment at maturity of only 15% of
your principal.
The terms of the Buffered PLUS differ from those of ordinary debt securities in that the Buffered PLUS do not
pay interest, and provide a minimum payment at maturity of only 15% of the stated principal amount of the Buffered PLUS, subject
to our credit risk. If the final share price is less than 85% of the initial share price, you will receive for each Buffered PLUS
that you hold a payment at maturity that is less than the stated principal amount of each Buffered PLUS by an amount proportionate
to the decline in the closing value of the underlying commodity shares from the initial share price, plus $1.50 per Buffered PLUS.
Accordingly, investors may lose up to 85% of the stated principal amount of the Buffered PLUS.

 

§ The appreciation potential of the Buffered PLUS is limited by the maximum payment at maturity.
The appreciation potential of the Buffered PLUS is limited by the maximum payment at maturity of $15.20 per Buffered PLUS, or 152.00%
of the stated principal amount. Although the leverage factor provides 300% exposure to any increase in the final share price over
the initial share price, because the payment at maturity will be limited to 152.00% of the stated principal amount for the Buffered
PLUS, any increase in the final share price over the initial share price by more than approximately 17.333% of the initial share
price will not further increase the return on the Buffered PLUS.

 

§ The market price of the Buffered PLUS will be influenced by many unpredictable factors.
Several factors, many of which are beyond our control, will influence the value of the Buffered PLUS in the secondary market and
the price at which MS & Co. may be willing to purchase or sell the Buffered PLUS in the secondary market, including the trading
price, volatility (frequency and magnitude of changes in value) and dividends of the underlying commodity shares, interest and
yield rates in the market, time remaining until the Buffered PLUS mature, geopolitical conditions and economic, financial, political
and regulatory or judicial events and any actual or anticipated changes in our credit ratings or credit spreads. The price of the
underlying commodity shares may be, and has recently been, extremely volatile, and we can give you no assurance that such volatility
will lessen. See “iShares® Silver Trust Overview” below. You may receive less, and possibly significantly
less, than the stated principal amount per Buffered PLUS if you try to sell your Buffered PLUS prior to maturity.

 

§ Single commodity prices tend to be more volatile than, and may not correlate with, the prices
of commodities generally.
The iShares® Silver Trust is linked exclusively to the price of silver and not to
a diverse basket of commodities or a broad-based commodity index. The price of silver may not correlate with, and may diverge significantly
from, the prices of commodities generally. Because the Buffered PLUS are linked to underlying commodity shares which reflect the
performance of the price of a single commodity, they carry greater risk and may be more volatile than a security linked to the
prices of multiple commodities or a broad-based commodity index. The price of silver may be, and has recently been, highly volatile,
and we can give you no assurance that such volatility will lessen.

 

§ The Buffered PLUS are subject to risks associated with silver. The iShares®
Silver Trust seeks to reflect generally the performance of the price of silver, less the iShares® Silver Trust’s
expenses and liabilities. The price of silver is primarily affected by global demand for and supply of silver. Silver prices can
fluctuate widely and may be affected by numerous factors. These include general economic trends, technical developments, substitution
issues and regulation, as well as specific factors including industrial and jewelry demand, expectations with respect to the rate
of inflation, the relative strength of the U.S. dollar (as the currency in which the price of silver is generally quoted) and other
currencies, interest rates, central bank sales, forward sales by producers, global or regional political or economic events and
production costs and disruptions in major silver-producing countries, such as Mexico, China and Peru. The demand for and supply
of silver affect silver prices, but not necessarily in the same manner as supply and demand affect the prices of other commodities.
The supply of silver consists of a combination of new mine production and existing stocks of bullion and fabricated silver held
by governments, public and private financial institutions, industrial organizations and private individuals. In addition, the price
of silver has on occasion been subject to very rapid short-term changes due to speculative activities. From time to time, above-ground
inventories of silver may also influence the market. The major end-uses for silver include industrial applications, jewelry and
silverware. It is not possible to predict the aggregate effect of any or all of these factors.

 

§ There are risks relating to trading of commodities on the London Bullion Market Association.
The investment objective of the iShares® Silver Trust is to reflect generally the performance of the price of
silver, less the iShares® Silver Trust’s expenses and liabilities. The price of silver is determined by the
LBMA or an independent service-provider appointed by the LBMA. The LBMA is a self-regulatory association of bullion market participants.
Although all market-

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

making members of the LBMA are supervised
by the Bank of England and are required to satisfy a capital adequacy test, the LBMA itself is not a regulated entity. If the LBMA
should cease operations, or if bullion trading should become subject to a value added tax or other tax or any other form of regulation
not currently in place, the role of LBMA prices as a global benchmark for the value of silver may be adversely affected. The LBMA
is a principals’ market that operates in a manner more closely analogous to an over-the-counter physical commodity market
than a regulated futures markets, and certain features of U.S. futures contracts are not present in the context of LBMA trading.
For example, there are no daily price limits on the LBMA that would otherwise restrict fluctuations in the prices of LBMA contracts.
In a declining market, it is possible that prices would continue to decline without limitation within a trading day or over a period
of trading days. The LBMA may alter, discontinue or suspend calculation or dissemination of the LBMA silver price, which could
adversely affect the value of the Buffered PLUS. The LBMA, or an independent service-provider appointed by the LBMA, will have
no obligation to consider your interests in calculating or revising LBMA prices.

 

§ The Buffered PLUS are subject to our credit risk, and any actual or anticipated changes to
our credit ratings or credit spreads may adversely affect the market value of the Buffered PLUS.
You are dependent on our ability
to pay all amounts due on the Buffered PLUS at maturity and therefore you are subject to our credit risk. If we default on our
obligations under the Buffered PLUS, your investment would be at risk and you could lose some or all of your investment. As a result,
the market value of the Buffered PLUS prior to maturity will be affected by changes in the market’s view of our creditworthiness.
Any actual or anticipated decline in our credit ratings or increase in the credit spreads charged by the market for taking our
credit risk is likely to adversely affect the market value of the Buffered PLUS.

 

§ As a finance subsidiary, MSFL has no independent operations and will have no independent assets.
As a finance subsidiary, MSFL has no independent operations beyond the issuance and administration of its securities and will
have no independent assets available for distributions to holders of MSFL securities if they make claims in respect of such securities
in a bankruptcy, resolution or similar proceeding. Accordingly, any recoveries by such holders will be limited to those available
under the related guarantee by Morgan Stanley and that guarantee will rank pari passu with all other unsecured, unsubordinated
obligations of Morgan Stanley. Holders will have recourse only to a single claim against Morgan Stanley and its assets under the
guarantee. Holders of securities issued by MSFL should accordingly assume that in any such proceedings they would not have any
priority over and should be treated pari passu with the claims of other unsecured, unsubordinated creditors of Morgan Stanley,
including holders of Morgan Stanley-issued securities.

 

§ The amount payable on the Buffered PLUS is not linked to the value of the underlying commodity
shares at any time other than the valuation date.
The final share price will be based on the closing price on the valuation
date, subject to postponement for non-trading days and certain market disruption events. Even if the value of the underlying commodity
shares appreciate prior to the valuation date but then drop by the valuation date by more than 15%, the payment at maturity will
be less, and may be significantly less, than it would have been had the payment at maturity been linked to the value of the underlying
commodity shares prior to such drop. Although the actual value of the underlying commodity shares on the stated maturity date or
at other times during the term of the Buffered PLUS may be higher than the closing price on the valuation date, the payment at
maturity will be based solely on the closing price on the valuation date.

 

§ Suspensions or disruptions of market trading in commodity and related futures markets could
adversely affect the price of the Buffered PLUS.
The commodity markets are subject to temporary distortions or other disruptions
due to various factors, including the lack of liquidity in the markets, the participation of speculators and government regulation
and intervention. In addition, U.S. futures exchanges and some foreign exchanges have regulations that limit the amount of fluctuation
in futures contract prices which may occur during a single business day. These limits are generally referred to as “daily
price fluctuation limits” and the maximum or minimum price of a contract on any given day as a result of these limits is
referred to as a “limit price.” Once the limit price has been reached in a particular contract, no trades may be made
at a different price. Limit prices have the effect of precluding trading in a particular contract or forcing the liquidation of
contracts at disadvantageous times or prices. These circumstances could adversely affect the value of the commodity that constitutes
the underlying commodity shares, and, therefore, the value of the Buffered PLUS.

 

§ Investing in the Buffered PLUS is not equivalent to investing in the underlying commodity
shares or in the commodity composing the underlying commodity shares. 
Investing in the Buffered PLUS is not equivalent
to investing in the underlying commodity shares or in the commodity that constitutes the underlying commodity shares. Investors
in the Buffered PLUS will not have voting rights or rights to receive distributions or any other rights with respect to the underlying
commodity that constitutes the underlying commodity shares.

 

§ The performance and market price of the underlying commodity shares, particularly during periods
of market volatility, may not correlate with the performance of their commodity or the net asset value per share of the underlying
commodity shares.
The underlying commodity shares do not fully replicate the performance of their underlying commodity due
to the fees and expenses charged by the underlying commodity shares or by restrictions on

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

access to the underlying commodity
due to other circumstances. The underlying commodity shares do not generate any income, and as the underlying commodity shares
regularly sell their underlying commodity to pay for ongoing expenses, the amount of their underlying commodity represented by
each share gradually declines over time. The underlying commodity shares sell their underlying commodity to pay expenses on an
ongoing basis irrespective of whether the trading price of the shares rises or falls in response to changes in the price of their
underlying commodity. The sale by the underlying commodity shares of their underlying commodity to pay expenses at a time of relatively
low prices for their underlying commodity could adversely affect the value of the Buffered PLUS. Additionally, there is a risk
that part or all of the holdings of the underlying commodity shares in their underlying commodity could be lost, damaged or stolen
due to war, terrorism, theft, natural disaster or otherwise. Finally, because the underlying commodity shares are traded on an
exchange and are subject to market supply and investor demand, the market price of the underlying commodity shares may differ from
the net asset value per share of such underlying commodity shares.

 

In particular, during periods of
market volatility, or unusual trading activity, the underlying commodity underlying the underlying commodity shares may be disrupted
or limited, or such underlying commodity may be unavailable in the secondary market. Under these circumstances, the liquidity of
the underlying commodity shares may be adversely affected, market participants may be unable to calculate accurately the net asset
value per share of the underlying commodity shares, and their ability to create and redeem shares of the underlying commodity shares
may be disrupted. Under these circumstances, the market price of shares of the underlying commodity shares may vary substantially
from the net asset value per share of the underlying commodity shares or the performance of their underlying commodity.

 

For all of the foregoing reasons,
the performance of the underlying commodity shares may not correlate with the performance of their underlying commodity or the
net asset value per share of such underlying commodity shares. Any of these events could materially and adversely affect the price
of the underlying commodity shares and, therefore, the value of the Buffered PLUS. Additionally, if market volatility or these
events were to occur on the valuation date, the calculation agent would maintain discretion to determine whether such market volatility
or events have caused a market disruption event to occur, and such determination would affect the payment at maturity of the Buffered
PLUS. If the calculation agent determines that no market disruption event has taken place, the payment at maturity would be based
solely on the published closing price per share of the underlying commodity shares on the valuation date, even if the underlying
commodity shares are underperforming their underlying commodity and/or trading below the net asset value per share of such underlying
commodity shares.

 

§ The rate we are willing to pay for securities of this type, maturity and issuance size is
likely to be lower than the rate implied by our secondary market credit spreads and advantageous to us. Both the lower rate and
the inclusion of costs associated with issuing, selling, structuring and hedging the Buffered PLUS in the original issue price
reduce the economic terms of the Buffered PLUS, cause the estimated value of the Buffered PLUS to be less than the original issue
price and will adversely affect secondary market prices.
Assuming no change in market conditions or any other relevant factors,
the prices, if any, at which dealers, including MS & Co., may be willing to purchase the Buffered PLUS in secondary market
transactions will likely be significantly lower than the original issue price, because secondary market prices will exclude the
issuing, selling, structuring and hedging-related costs that are included in the original issue price and borne by you and because
the secondary market prices will reflect our secondary market credit spreads and the bid-offer spread that any dealer would charge
in a secondary market transaction of this type as well as other factors.

 

The inclusion of the costs of issuing,
selling, structuring and hedging the Buffered PLUS in the original issue price and the lower rate we are willing to pay as issuer
make the economic terms of the Buffered PLUS less favorable to you than they otherwise would be.

 

However, because the costs associated
with issuing, selling, structuring and hedging the Buffered PLUS are not fully deducted upon issuance, for a period of up to 6
months following the issue date, to the extent that MS & Co. may buy or sell the Buffered PLUS in the secondary market, absent
changes in market conditions, including those related to the underlying commodity shares, and to our secondary market credit spreads,
it would do so based on values higher than the estimated value, and we expect that those higher values will also be reflected in
your brokerage account statements.

 

§ The estimated value of the Buffered PLUS is determined by reference to our pricing and valuation
models, which may differ from those of other dealers and is not a maximum or minimum secondary market price.
These pricing
and valuation models are proprietary and rely in part on subjective views of certain market inputs and certain assumptions about
future events, which may prove to be incorrect. As a result, because there is no market-standard way to value these types of securities,
our models may yield a higher estimated value of the Buffered PLUS than those generated by others, including other dealers in the
market, if they attempted to value the Buffered PLUS. In addition, the estimated value on the pricing date does not represent a
minimum or maximum price at which dealers, including MS & Co., would be willing to purchase your Buffered PLUS in the secondary
market (if any exists) at any time. The value of your Buffered

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

PLUS at any time after the date
of this document will vary based on many factors that cannot be predicted with accuracy, including our creditworthiness and changes
in market conditions. See also “The market price of the Buffered PLUS will be influenced by many unpredictable factors”
above.

 

§ The antidilution adjustments the calculation agent is required to make do not cover every
event that could affect the shares of the iShares® Silver Trust
. MS & Co., as calculation agent, will adjust
the adjustment factor for certain events affecting the shares of the iShares®
Silver Trust
. However, the calculation agent will not make an adjustment for every event that could affect the shares of
the iShares® Silver Trust. If an event occurs that does not require the
calculation agent to adjust the adjustment factor, the market price of the Buffered PLUS may be materially and adversely affected.

 

§ The Buffered PLUS will not be listed on any securities exchange and secondary trading may
be limited.
The Buffered PLUS will not be listed on any securities exchange. Therefore, there may be little or no secondary
market for the Buffered PLUS. MS & Co. may, but is not obligated to, make a market in the Buffered PLUS and, if it once chooses
to make a market, may cease doing so at any time. When it does make a market, it will generally do so for transactions of routine
secondary market size at prices based on its estimate of the current value of the Buffered PLUS, taking into account its bid/offer
spread, our credit spreads, market volatility, the notional size of the proposed sale, the cost of unwinding any related hedging
positions, the time remaining to maturity and the likelihood that it will be able to resell the Buffered PLUS. Even if there is
a secondary market, it may not provide enough liquidity to allow you to trade or sell the Buffered PLUS easily. Since other broker-dealers
may not participate significantly in the secondary market for the Buffered PLUS, the price at which you may be able to trade your
Buffered PLUS is likely to depend on the price, if any, at which MS & Co. is willing to transact. If, at any time, MS &
Co. were to cease making a market in the Buffered PLUS, it is likely that there would be no secondary market for the Buffered PLUS.
Accordingly, you should be willing to hold your Buffered PLUS to maturity.

 

§ The calculation agent, which is a subsidiary of Morgan Stanley and an affiliate of MSFL, will
make determinations with respect to the Buffered PLUS.
As calculation agent, MS & Co. will determine the initial share
price and the final share price, and will calculate the amount of cash you receive at maturity. Moreover, certain determinations
made by MS & Co. in its capacity as calculation agent, may require it to exercise discretion and make subjective judgements,
such as with respect to the occurrence or non-occurrence of market disruption events or calculation of the final share price in
the event of a market disruption event. These potentially subjective determinations may
adversely affect the payout to you at maturity. For further information regarding these type of determinations, see “Description
of PLUS—Postponement of Valuation Date(s)” and “—Calculation Agent and Calculations” in the accompanying
prospectus supplement. In addition, MS & Co. has determined the estimated value of the Buffered PLUS on the pricing date.

 

§ Hedging and trading activity by our affiliates could potentially adversely affect the value
of the Buffered PLUS.
One or more of our affiliates and/or third-party dealers expect to carry out hedging activities related
to the Buffered PLUS (and to other instruments linked to the underlying commodity shares and the underlying commodity), including
trading in the underlying commodity shares. As a result, these entities may be unwinding or adjusting hedge positions during the
term of the Buffered PLUS, and the hedging strategy may involve greater and more frequent dynamic adjustments to the hedge as the
valuation date approaches. Some of our affiliates also trade the underlying commodity shares and other financial instruments related
to the underlying commodity shares and the underlying commodity on a regular basis as part of their general broker-dealer and other
businesses. Any of these hedging or trading activities on or prior to the pricing date could potentially increase the initial share
price of the underlying commodity shares, and, therefore, could increase the price at or above which the underlying commodity shares
must close on the valuation date so that investors do not suffer a loss on their initial investment in the Buffered PLUS. Additionally,
such hedging or trading activities during the term of the Buffered PLUS, including on the valuation date, could adversely affect
the value of the underlying commodity shares on the valuation date, and, accordingly, the amount of cash an investor will receive
at maturity.

 

§ The U.S. federal income tax consequences of an investment in the Buffered PLUS are uncertain.
Please read the discussion under “Additional Information—Tax considerations” in this document and the discussion
under “United States Federal Taxation” in the accompanying prospectus supplement for PLUS (together, the “Tax
Disclosure Sections”) concerning the U.S. federal income tax consequences of an investment in the Buffered PLUS. As discussed
in the Tax Disclosure Sections, there is a substantial risk that the “constructive ownership” rule could apply, in
which case all or a portion of any long-term capital gain recognized by a U.S. Holder could be recharacterized as ordinary income
and an interest charge could be imposed. In addition, long-term capital gain that a U.S. Holder would otherwise recognize in respect
of the Buffered PLUS up to the amount of the “net underlying long-term capital gain” could, if the U.S. Holder is an
individual or other non-corporate investor, be subject to tax at the higher rates applicable to “collectibles” instead
of the general rates that apply to long-term capital gain. If the Internal Revenue Service (the “IRS”) were successful
in asserting an alternative treatment, the timing and character of income on the Buffered PLUS might differ significantly from
the tax treatment described in the Tax Disclosure Sections. For example, under one possible treatment, the IRS could seek to

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

recharacterize the Buffered PLUS
as debt instruments. In that event, U.S. Holders would be required to accrue into income original issue discount on the Buffered
PLUS every year at a “comparable yield” determined at the time of issuance and recognize all income and gain in respect
of the Buffered PLUS as ordinary income. Additionally, as discussed under “United States Federal Taxation—FATCA”
in the accompanying prospectus supplement for PLUS, the withholding rules commonly referred to as “FATCA” would apply
to the Buffered PLUS if they were recharacterized as debt instruments. However, recently proposed regulations (the preamble to
which specifies that taxpayers are permitted to rely on them pending finalization) eliminate the withholding requirement on payments
of gross proceeds of a taxable disposition (other than amounts treated as “FDAP income,” as defined in the accompanying
prospectus supplement for PLUS). The risk that financial instruments providing for buffers, triggers or similar downside protection
features, such as the Buffered PLUS, would be recharacterized as debt is greater than the risk of recharacterization for comparable
financial instruments that do not have such features. We do not plan to request a ruling from the IRS regarding the tax treatment
of the Buffered PLUS, and the IRS or a court may not agree with the tax treatment described in the Tax Disclosure Sections.

 

In 2007, the U.S. Treasury Department
and the IRS released a notice requesting comments on the U.S. federal income tax treatment of “prepaid forward contracts”
and similar instruments. The notice focuses in particular on whether to require holders of these instruments to accrue income over
the term of their investment. It also asks for comments on a number of related topics, including the character of income or loss
with respect to these instruments; whether short-term instruments should be subject to any such accrual regime; the relevance of
factors such as the exchange-traded status of the instruments and the nature of the underlying property to which the instruments
are linked; the degree, if any, to which income (including any mandated accruals) realized by non-U.S. investors should be subject
to withholding tax; and whether these instruments are or should be subject to the “constructive ownership” rule, as
discussed in this document. While the notice requests comments on appropriate transition rules and effective dates, any Treasury
regulations or other guidance promulgated after consideration of these issues could materially and adversely affect the tax consequences
of an investment in the Buffered PLUS, possibly with retroactive effect. Both U.S. and Non-U.S. Holders should consult their tax
advisers regarding the U.S. federal income tax consequences of an investment in the Buffered PLUS, including possible alternative
treatments, the potential application of the constructive ownership rule, the issues presented by this notice and any tax consequences
arising under the laws of any state, local or non-U.S. taxing jurisdiction.

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

iShares® Silver Trust Overview

 

The iShares® Silver Trust (the “Silver
Trust”) is an investment trust sponsored by iShares® Delaware Trust Sponsor LLC , which seeks to provide
investment results that reflect the performance of the price of silver, less the iShares® Silver Trust’s
expenses and liabilities. The assets of the iShares® Silver Trust consists primarily of silver held by a custodian
on behalf of the iShares® Silver Trust. Information provided to or filed with the Securities and Exchange Commission
(the “Commission”) by the iShares® Silver Trust pursuant to the Securities Act of 1933 can be located
by reference to Commission file number 001-32863 through the Commission’s website at www.sec.gov. In addition, information
may be obtained from other publicly available sources. Neither the issuer nor the agent makes any representation that any
such publicly available information regarding the iShares® Silver Trust is accurate or complete.

 

All information contained in this document regarding the iShares® Silver
Trust (the “Silver Trust”), has been derived from publicly available information, without independent verification.
This information reflects the policies of, and is subject to change by, iShares® Delaware Trust Sponsor LLC,
a subsidiary of BlackRock, Inc., the sponsor of the Silver Trust. The Bank of New York Mellon is the trustee of the Silver Trust,
and JPMorgan Chase Bank, N.A. is the custodian of the Silver Trust. Shares of the Silver Trust trades under the ticker symbol “SLV”
on NYSE Arca, Inc.

 

The Silver Trust issues shares in exchange for deposits of silver
and distributes silver in connection with the redemption of shares. The shares of the Silver Trust are intended to constitute a
simple and cost-effective means of making an investment similar to an investment in silver.

 

The Silver Trust does not engage in any activity designed to
derive a profit from changes in the price of silver. The Silver Trust’s only ordinary recurring expense is expected to be
the sponsor’s fee, which accrues daily at an annualized rate equal to 0.50% of the net asset value of the Silver Trust and
is payable monthly in arrears. The trustee of the Silver Trust will, when directed by the sponsor of the Silver Trust, and, in
the absence of such direction, may in its discretion, sell silver in such quantity and at such times as may be necessary to permit
payment of the Silver Trust sponsor’s fee and of Silver Trust expenses or liabilities not assumed by the sponsor. As a result
of the recurring sales of silver necessary to pay the Silver Trust sponsor’s fee and the Silver Trust expenses or liabilities
not assumed by the Silver Trust sponsor, the net asset value of the Silver Trust will decrease over the life of the Silver Trust.

 

Information as of market close on September 23, 2020:

 

Bloomberg
Ticker Symbol:
SLV UP
Current Share
Price:
$21.17
52 Weeks Ago: $17.51
52 Week High
(on 8/10/2020):
$27.00
52 Week Low
(on 3/18/2020):
$11.21

 

The following graph sets forth
the daily closing price of the underlying commodity shares for the period from January 1, 2015 through September 23, 2020. The
related table sets forth the published high and low closing prices, as well as the end-of-quarter closing prices, of the underlying
commodity shares for each quarter in the same period. The closing price of the underlying commodity shares on September 23, 2020
was $21.17. We obtained the information in the graph and table below from Bloomberg Financial Markets, without independent verification.
The underlying commodity shares have at times experienced periods of high volatility. The historical prices of the underlying commodity
shares should not be taken as an indication of future performance, and no assurance can be given as to the closing price of the
underlying commodity shares on the valuation date.

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

Shares of the iShares®
Silver Trust
Daily Closing Prices
January 1, 2015 to September 23, 2020

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

iShares®
Silver Trust (CUSIP 46428Q109)
High
($)
Low
($)
Period
End ($)
2015      
First Quarter 17.61 14.84 15.93
Second
Quarter
16.89 15.03 15.03
hird
Quarter
14.99 13.56 13.87
Fourth Quarter 15.42 13.06 13.19
2016      
First Quarter 15.16 13.17 14.68
Second
Quarter
17.87 14.20 17.87
Third Quarter 19.60 17.62 18.20
Fourth Quarter 17.87 14.91 15.11
2017      
First Quarter   17.44 15.44 17.25
Second Quarter 17.53 15.30 15.71
Third Quarter 17.10 14.73 15.74
Fourth Quarter 16.41 14.85 15.99
2018      
First Quarter   16.56 15.28 15.41
Second Quarter 16.26 15.07 15.15
Third Quarter 15.17 13.23 13.73
Fourth Quarter 14.52 13.15 14.52
2019      
First Quarter   15.07 14.07 14.18
Second Quarter 14.46 13.46 14.33
Third Quarter 18.34 14.05 15.92
Fourth Quarter 16.92 15.48 16.68
2020      
First Quarter 17.40 11.21 13.05
Second Quarter 17.10 13.02 17.01
Third Quarter (through September 23, 2020) 27.00 16.71 21.17

 

This document relates only to the Buffered PLUS offered hereby
and does not relate to the underlying commodity shares. We have derived all disclosures contained in this document regarding the
Silver Trust from the publicly available documents described in the preceding paragraph. In connection with the offering of the
Buffered PLUS, neither we nor the agent has participated in the preparation of such documents or made any due diligence inquiry
with respect to the Silver Trust. Neither we nor the agent makes any representation that such publicly available documents or any
other publicly available information regarding the Silver Trust is accurate or complete. Furthermore, we cannot give any assurance
that all events occurring prior to the date hereof (including events that would affect the accuracy or completeness of the publicly
available documents described in the preceding paragraph) that would affect the trading price of the underlying commodity shares
(and therefore the price of the underlying commodity shares at the time we price the Buffered PLUS) have been publicly disclosed.
Subsequent disclosure of any such events or the disclosure of or failure to disclose material future events concerning the Silver
Trust could affect the value received at maturity with respect to the Buffered PLUS and therefore the value of the Buffered PLUS.

 

Neither we nor any of our affiliates makes any representation
to you as to the performance of the underlying commodity shares.

 

We and/or our affiliates may presently or from time to time engage
in business with the Silver Trust.  In the course of such business, we and/or our affiliates may acquire non-public information
with respect to the Silver Trust, and neither we nor any of our affiliates undertakes to disclose any such information to you.  In
addition, one or more of our affiliates may publish research reports with respect to the underlying commodity shares.  The
statements in the preceding two sentences are not intended to affect the rights of investors in the Buffered PLUS under the securities
laws.  As a prospective purchaser of the

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

Buffered PLUS, you should undertake an independent investigation
of the Silver Trust as in your judgment is appropriate to make an informed decision with respect to an investment linked to the
underlying commodity shares.

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

Additional Terms of the Buffered PLUS

 

Please read this information
in conjunction with the summary terms on the front cover of this document.

 

Additional
Terms:
 
If the terms described herein are inconsistent with those described in the accompanying prospectus supplement or prospectus, the terms described herein shall control.
Underlying commodity: Silver
Denominations: $10 per Buffered PLUS and integral multiples thereof

Postponement of

maturity date: 

If the scheduled valuation date is not a trading day or if a market disruption event occurs on that day so that the valuation date as postponed falls less than two business days prior to the scheduled maturity date, the maturity date of the Buffered PLUS will be postponed to the second business day following that valuation date as postponed.
Postponement of valuation date: If a market disruption event occurs on the scheduled valuation date, the closing price for the underlying commodity shares for the valuation date will be the closing price on the next trading day on which no market disruption event occurs; provided that the closing price for the underlying commodity shares for the valuation date will not be determined on a date later than the fifth scheduled trading day following the valuation date and if such date is not a trading day or if there is a market disruption event with respect to such underlying commodity shares on such date, the calculation agent will determine the closing price for the underlying commodity shares for the valuation date as the arithmetic mean of the bid prices for the underlying commodity shares for such date obtained from as many recognized dealers in such underlying commodity shares, but not exceeding three, as will make such bid prices available to the calculation agent. Bids of MS & Co. or any of its affiliates may be included in the calculation of such mean, but only to the extent that any such bid is the highest of the bids obtained. If no bid prices are provided from any third-party dealers, the closing price will be determined by the calculation agent in its sole and absolute discretion (acting in good faith) taking into account any information that it deems relevant.
Closing price:

The closing price on any trading day means:

 

(i)         if the underlying commodity shares (or any such other security) are listed on a national securities exchange (other than the Nasdaq),
the last reported sale price, regular way, of the principal trading session on such day on the principal national securities exchange
registered under the Securities Exchange Act of 1934, as amended (the “Exchange Act”), on which the underlying commodity
ETF shares (or any such other security) are listed,

 

(ii)        if the underlying commodity shares (or any such other security) are securities of Nasdaq, the official closing price published
by Nasdaq on such day, or

 

(iii)       
if the underlying commodity shares (or any such other security) are not listed on any national securities exchange but are
included in the OTC Bulletin Board Service (the “OTC Bulletin Board”) operated by the Financial Industry
Regulatory Authority, Inc. (“FINRA”), the last reported sale price of the principal trading session on the OTC
Bulletin Board on such day.

 

If the underlying commodity shares (or any such other security)
are listed on any national securities exchange but the last reported sale price or the official closing price published by Nasdaq,
as applicable, is not available pursuant to the preceding sentence, then the closing price for one underlying commodity share (or
one unit of any such other security) on any trading day will mean the last reported sale price of the principal trading session
on the over-the-counter market as reported on Nasdaq or the OTC Bulletin Board on such day. If a market disruption event (as defined
below) occurs with respect to the underlying commodity shares (or any such other security) or the last reported sale price or the
official closing price published by Nasdaq, as applicable, for the underlying commodity shares (or any such other security) is
not available pursuant to the two preceding sentences, then the closing price for any trading day will be the mean, as determined
by the calculation agent, of the bid prices for the underlying commodity shares (or any such other security) for such trading day
obtained from as many recognized dealers in such security, but not exceeding three, as will make such bid prices available to the
calculation agent. Bids of MS & Co. and its successors or any of its affiliates may be included in the calculation of such
mean, but only to the extent that any such bid is the highest of the bids obtained. If no bid prices are provided from any third
party dealers, the closing price will be determined by the calculation agent in its sole and absolute discretion (acting in good
faith) taking into account any information that it deems relevant. The term “OTC Bulletin Board Service” will include
any successor service thereto. See “Discontinuance of the underlying commodity shares; alteration of method of calculation”
below.

Business day: Any day other than a Saturday or Sunday which is neither a legal holiday nor a day on which banking institutions are required or authorized by law or regulation to close in New York, New York or the city and state of our principal place of business or a day on which transactions in U.S. dollars are not conducted.

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

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Trading day: Trading day means a day, as determined by the calculation agent, on which NYSE Arca (or if NYSE Arca is no longer the principal exchange or trading market for the underlying commodity shares, such exchange or principal trading market for the underlying commodity shares that serves as the price-source for the underlying commodity shares) is open for trading during its regular trading session, notwithstanding such exchange or principal trading market closing prior to its scheduled closing time.
Market disruption event:

With respect to the underlying commodity shares, market disruption
event means:

 

(i)         the
occurrence of existence of any of:

 

a.    a suspension,
absence or material limitation of trading of the underlying commodity shares on the primary market for the underlying commodity
shares for more than two hours of trading or during the one-half hour period preceding the close of the principal trading session
in such market; or a breakdown or failure in the price and trade reporting systems of the primary market for the underlying commodity
shares as a result of which the reported trading prices for the underlying commodity shares during the last one-half hour preceding
the close of the principal trading session in such market are materially inaccurate; or the suspension, absence or material limitation
of trading on the primary market for trading in futures or options contracts related to the underlying commodity shares, if available,
during the one-half hour period preceding the close of the principal trading session in the applicable market; or

 

b.    a suspension,
material limitation or absence of trading on any major U.S. securities market for trading in futures or options contracts related
to the underlying commodity shares for more than two hours of trading or during the one-half hour period preceding the close of
the principal trading session on such market,

 

in each case as determined by the calculation agent
in its sole discretion, and

 

(ii)        a determination by the calculation agent in its sole discretion that any event described in clause (i) above materially interfered
with our ability or the ability of any of our affiliates to unwind or adjust all or a material portion of the hedge position with
respect to the securities.

 

For the purpose of determining whether a market disruption event
in respect of the underlying commodity shares has occurred: (1) a limitation on the hours or number of days of trading will not
constitute a market disruption event if it results from an announced change in the regular business hours of the market, (2) a
decision to permanently discontinue trading in the underlying commodity shares or in the relevant futures or options contract will
not constitute a market disruption event, (3) a suspension of trading in futures or options contracts on the underlying commodity
shares by the primary securities market trading in such contracts by reason of (a) a price change exceeding limits set by such
securities exchange or market, (b) an imbalance of orders relating to such contracts or (c) a disparity in bid and ask quotes relating
to such contracts will constitute a suspension, absence or material limitation of trading in futures or options contracts related
to the underlying commodity shares and (4) a “suspension, absence or material limitation of trading” on the primary
market on which futures or options contracts related to the underlying commodity shares are traded will not include any time when
such securities market is itself closed for trading under ordinary circumstances.

Discontinuance of the underlying commodity shares; alteration of method of calculation: If trading in the underlying commodity shares on every applicable national securities exchange is permanently discontinued or the underlying commodity shares are liquidated or otherwise terminated (a “discontinuance or liquidation event”), the Buffered PLUS will be deemed accelerated to the fifth business day following the date notice of such liquidation event is provided to holders of the underlying commodity shares under the terms of the underlying commodity shares (the date of such notice, the “liquidation announcement date” and the fifth business day following the liquidation announcement date, the “acceleration date”), and the payment to you on the acceleration date will be equal to the fair market value of the Buffered PLUS on the trading day immediately following the liquidation announcement date as determined by the calculation agent in its sole discretion based on its internal models, which will take into account the reasonable costs incurred by us or any of our affiliates in unwinding any related hedging arrangements.
Trustee: The Bank of New York Mellon
Calculation agent: MS & Co.
Issuer notice to registered security holders, the trustee and the depositary:

In the event that the maturity date is postponed due to postponement
of the valuation date, the issuer shall give notice of such postponement and, once it has been determined, of the date to which
the maturity date has been rescheduled (i) to each registered holder of the Buffered PLUS by mailing notice of such postponement
by first class mail, postage prepaid, to such registered holder’s last address as it shall appear upon the registry books,
(ii) to the trustee by facsimile confirmed by mailing such notice to the trustee by first class mail, postage prepaid, at its New
York office and (iii) to The Depository Trust Company (the “depositary”) by telephone or facsimile, confirmed by mailing
such notice to the depositary by first class mail, postage prepaid.  Any notice that is mailed to a registered holder of the
Buffered PLUS in the manner herein provided shall be conclusively presumed to have been duly given to such registered holder, whether
or not such registered holder receives the notice.  The issuer shall give such notice as promptly as possible, and in no case
later than (i) with respect to notice of postponement of the maturity date, the business day immediately preceding the

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

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scheduled maturity date and (ii) with respect to notice of the
date to which the maturity date has been rescheduled, the business day immediately following the actual valuation date for determining
the final share price.

 

The issuer shall, or shall cause the calculation agent to, (i)
provide written notice to the trustee and to the depositary of the amount of cash to be delivered with respect to each stated principal
amount of the Buffered PLUS, on or prior to 10:30 a.m. (New York City time) on the business day preceding the maturity date, and
(ii) deliver the aggregate cash amount due with respect to the Buffered PLUS to the trustee for delivery to the depositary, as
holder of the Buffered PLUS, on the maturity date.

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

Additional Information About the Buffered PLUS

 

Additional
Information:
 
Minimum
ticketing size:
$1,000 / 100 Buffered PLUS
Tax
considerations:

Although there is uncertainty
regarding the U.S. federal income tax consequences of an investment in the Buffered PLUS due to the lack of governing authority,
in the opinion of our counsel, Davis Polk & Wardwell LLP, under current law, and based on current market conditions, a Buffered
PLUS should be treated as a single financial contract that is an “open transaction” for U.S. federal income tax purposes.
However, because our counsel’s opinion is based in part on market conditions as of the date of this document, it is subject
to the confirmation on the pricing date.

 

Assuming this treatment
of the Buffered PLUS is respected and subject to the discussion in “United States Federal Taxation” in the accompanying
prospectus supplement for PLUS, the following U.S. federal income tax consequences should result based on current law:

 

§
   A U.S. Holder should not be required to recognize taxable income over the term of the Buffered PLUS prior to settlement,
other than pursuant to a sale or exchange.

 

§  Upon
sale, exchange or settlement of the Buffered PLUS, a U.S. Holder should recognize gain or loss equal to the difference between
the amount realized and the U.S. Holder’s tax basis in the Buffered PLUS. Subject to the discussion below concerning the
potential application of the “constructive ownership” rule, such gain or loss should be long-term capital gain or loss
if the investor has held the Buffered PLUS for more than one year, and short-term capital gain or loss otherwise.

 

Because the
Buffered PLUS are linked to shares of an exchange-traded fund, although the matter is not clear, there is a substantial risk that
an investment in the Buffered PLUS will be treated as a “constructive ownership transaction” under Section 1260 of
the Internal Revenue Code of 1986, as amended (the “Code”). If this treatment applies, all or a portion of any long-term
capital gain of the U.S. Holder in respect of the Buffered PLUS could be recharacterized as ordinary income (in which case an interest
charge will be imposed). As a result of certain features of the Buffered PLUS, including the leveraged upside payment, it is unclear
how to calculate the amount of gain that would be recharacterized if an investment in the Buffered PLUS were treated as a constructive
ownership transaction. In addition, long-term capital gain that a U.S. Holder would otherwise recognize in respect of the Buffered
PLUS up to the amount of the “net underlying long-term capital gain” could, if the U.S. Holder is an individual or
other non-corporate investor, be subject to tax at the higher rates applicable to “collectibles” instead of the general
rates that apply to long-term capital gain. Due to the lack of governing authority, our counsel is unable to opine as to whether
or how Section 1260 of the Code applies to the Buffered PLUS. U.S. investors should read the section entitled “United States
Federal Taxation—Tax Consequences to U.S. Holders—Possible Application of Section 1260 of the Code” in the accompanying
prospectus supplement for PLUS for additional information and consult their tax advisers regarding the potential application of
the “constructive ownership” rule.

 

In 2007,
the U.S. Treasury Department and the Internal Revenue Service (the “IRS”) released a notice requesting comments on
the U.S. federal income tax treatment of “prepaid forward contracts” and similar instruments. The notice focuses in
particular on whether to require holders of these instruments to accrue income over the term of their investment. It also asks
for comments on a number of related topics, including the character of income or loss with respect to these instruments; whether
short-term instruments should be subject to any such accrual regime; the relevance of factors such as the exchange-traded status
of the instruments and the nature of the underlying property to which the instruments are linked; the degree, if any, to which
income (including any mandated accruals) realized by non-U.S. investors should be subject to withholding tax; and whether these
instruments are or should be subject to the “constructive ownership” rule, as discussed above. While the notice requests
comments on appropriate transition rules and effective dates, any Treasury regulations or other guidance promulgated after consideration
of these issues could materially and adversely affect the tax consequences of an investment in the Buffered PLUS, possibly with
retroactive effect.

 

In addition,
Section 871(m) of the Code and Treasury regulations promulgated thereunder (“Section 871(m)”) generally impose a 30%
(or a lower applicable treaty rate) withholding tax on dividend equivalents paid or deemed paid to Non-U.S. Holders with respect
to certain financial instruments linked to U.S. equities or indices that include U.S. equities (each, an “Underlying Security”).
Subject to certain exceptions, Section 871(m) generally applies to securities that substantially replicate the economic performance
of one or more Underlying Securities, as determined based on tests set forth in the applicable Treasury regulations (a “Specified
Security”). However, pursuant to an IRS notice, Section 871(m) will not apply to securities issued before January 1, 2023
that do not have a delta of one with respect to any Underlying Security. Based on the terms of the Buffered PLUS and current market
conditions, we expect that the Buffered PLUS will not have a delta of one with respect to any Underlying Security on the pricing
date. However, we will provide an updated determination in the final pricing supplement. Assuming that the Buffered PLUS do not
have a delta of one with respect to any

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

 

Underlying
Security, our counsel is of the opinion that the Buffered PLUS should not be Specified Securities and, therefore, should not be
subject to Section 871(m).

 

Our determination
is not binding on the IRS, and the IRS may disagree with this determination. Section 871(m) is complex and its application may
depend on your particular circumstances, including whether you enter into other transactions with respect to an Underlying Security.
If withholding is required, we will not be required to pay any additional amounts with respect to the amounts so withheld. You
should consult your tax adviser regarding the potential application of Section 871(m) to the Buffered PLUS.

 

Both U.S.
and non-U.S. investors considering an investment in the Buffered PLUS should read the discussion under “Risk Factors”
in this document and the discussion under “United States Federal Taxation” in the accompanying prospectus supplement
for PLUS and consult their tax advisers regarding all aspects of the U.S. federal income tax consequences of an investment in the
Buffered PLUS, including possible alternative treatments, the potential application of the constructive ownership rule, the issues
presented by the aforementioned notice and any tax consequences arising under the laws of any state, local or non-U.S. taxing jurisdiction.

 

The discussion
in the preceding paragraphs under “Tax considerations” and the discussion contained in the section entitled “United
States Federal Taxation” in the accompanying prospectus supplement for PLUS, insofar as they purport to describe provisions
of U.S. federal income tax laws or legal conclusions with respect thereto, constitute the full opinion of Davis Polk & Wardwell
LLP regarding the material U.S. federal tax consequences of an investment in the Buffered PLUS.


Use of proceeds and hedging:

The proceeds from the sale of the Buffered PLUS will be used
by us for general corporate purposes. We will receive, in aggregate, $10 per Buffered PLUS issued, because, when we enter into
hedging transactions in order to meet our obligations under the Buffered PLUS, our hedging counterparty will reimburse the cost
of the agent’s commissions. The costs of the Buffered PLUS borne by you and described on page 2 above comprise the agent’s
commissions and the cost of issuing, structuring and hedging the Buffered PLUS.

 

On or prior to the pricing date, we will hedge our anticipated
exposure in connection with the Buffered PLUS, by entering into hedging transactions with our affiliates and/or third-party dealers.
We expect our hedging counterparties to take positions in underlying commodity shares, futures and options contracts on the underlying
commodity shares, or positions in any other available securities or instruments that they may wish to use in connection with such
hedging. Such purchase activity could potentially increase the price of the underlying commodity shares on the pricing date, and,
therefore, could increase the price at or above which the underlying commodity shares must close on the valuation date so that
investors do not suffer a loss on their initial investment in the Buffered PLUS. In addition, through our affiliates, we are likely
to modify our hedge position throughout the term of the Buffered PLUS, including on the valuation date, by purchasing and selling
the underlying commodity shares, futures or options contracts on the underlying commodity shares or positions in any other available
securities or instruments that we may wish to use in connection with such hedging activities. As a result, these entities may be
unwinding or adjusting hedge positions during the term of the Buffered PLUS, and the hedging strategy may involve greater and more
frequent dynamic adjustments to the hedge as the valuation date approaches. We cannot give any assurance that our hedging activities
will not affect the value of the underlying commodity shares, and, therefore, adversely affect the value of the Buffered PLUS or
the payment you will receive at maturity. For further information on our use of proceeds and hedging, see “Use of Proceeds
and Hedging” in the accompanying prospectus supplement for PLUS.

Benefit
plan investor considerations:

Each fiduciary of a pension, profit-sharing or other employee
benefit plan subject to Title I of the Employee Retirement Income Security Act of 1974, as amended (“ERISA”) (a “Plan”),
should consider the fiduciary standards of ERISA in the context of the Plan’s particular circumstances before authorizing
an investment in the Buffered PLUS. Accordingly, among other factors, the fiduciary should consider whether the investment would
satisfy the prudence and diversification requirements of ERISA and would be consistent with the documents and instruments governing
the Plan.

 

In addition, we and certain of our affiliates, including MS &
Co., may each be considered a “party in interest” within the meaning of ERISA, or a “disqualified person”
within the meaning of the Internal Revenue Code of 1986, as amended (the “Code”), with respect to many Plans, as well
as many individual retirement accounts and Keogh plans (such accounts and plans, together with other plans, accounts and arrangements
subject to Section 4975 of the Code, also “Plans”). ERISA Section 406 and Section 4975 of the Code generally prohibit
transactions between Plans and parties in interest or disqualified persons. Prohibited transactions within the meaning of ERISA
or the Code would likely arise, for example, if the Buffered PLUS are acquired by or with the assets of a Plan with respect to
which MS & Co. or any of its affiliates is a service provider or other party in interest, unless the Buffered PLUS are acquired
pursuant to an exemption from the “prohibited transaction” rules. A violation of these “prohibited transaction”
rules could result in an excise tax or other liabilities under ERISA and/or Section 4975 of the Code for those persons, unless
exemptive relief is available under an applicable statutory or administrative exemption.

 

The U.S. Department of Labor has issued five prohibited transaction
class exemptions (“PTCEs”) that may provide exemptive relief for direct or indirect prohibited transactions resulting
from the purchase or

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

 

holding of the Buffered PLUS. Those class exemptions are PTCE
96-23 (for certain transactions determined by in-house asset managers), PTCE 95-60 (for certain transactions involving insurance
company general accounts), PTCE 91-38 (for certain transactions involving bank collective investment funds), PTCE 90-1 (for certain
transactions involving insurance company separate accounts) and PTCE 84-14 (for certain transactions determined by independent
qualified professional asset managers). In addition, ERISA Section 408(b)(17) and Section 4975(d)(20) of the Code provide an exemption
for the purchase and sale of securities and the related lending transactions, provided that neither the issuer of the securities
nor any of its affiliates has or exercises any discretionary authority or control or renders any investment advice with respect
to the assets of the Plan involved in the transaction and provided further that the Plan pays no more, and receives no less, than
“adequate consideration” in connection with the transaction (the so-called “service provider” exemption).
There can be no assurance that any of these class or statutory exemptions will be available with respect to transactions involving
the Buffered PLUS.

 

Because we may be considered a party in interest with respect
to many Plans, the Buffered PLUS may not be purchased, held or disposed of by any Plan, any entity whose underlying assets include
“plan assets” by reason of any Plan’s investment in the entity (a “Plan Asset Entity”) or any person
investing “plan assets” of any Plan, unless such purchase, holding or disposition is eligible for exemptive relief,
including relief available under PTCEs 96-23, 95-60, 91-38, 90-1, 84-14 or the service provider exemption or such purchase, holding
or disposition is otherwise not prohibited. Any purchaser, including any fiduciary purchasing on behalf of a Plan, transferee or
holder of the Buffered PLUS will be deemed to have represented, in its corporate and its fiduciary capacity, by its purchase and
holding of the Buffered PLUS that either (a) it is not a Plan or a Plan Asset Entity and is not purchasing such Buffered PLUS on
behalf of or with “plan assets” of any Plan or with any assets of a governmental, non-U.S. or church plan that is subject
to any federal, state, local or non-U.S. law that is substantially similar to the provisions of Section 406 of ERISA or Section
4975 of the Code (“Similar Law”) or (b) its purchase, holding and disposition of these Buffered PLUS will not constitute
or result in a non-exempt prohibited transaction under Section 406 of ERISA or Section 4975 of the Code or violate any Similar
Law.

 

Due to the complexity of these rules and the penalties that may
be imposed upon persons involved in non-exempt prohibited transactions, it is particularly important that fiduciaries or other
persons considering purchasing the Buffered PLUS on behalf of or with “plan assets” of any Plan consult with their
counsel regarding the availability of exemptive relief.

 

The Buffered PLUS are contractual financial instruments. The
financial exposure provided by the Buffered PLUS is not a substitute or proxy for, and is not intended as a substitute or proxy
for, individualized investment management or advice for the benefit of any purchaser or holder of the Buffered PLUS. The Buffered
PLUS have not been designed and will not be administered in a manner intended to reflect the individualized needs and objectives
of any purchaser or holder of the Buffered PLUS.

 

Each purchaser or holder of any Buffered PLUS acknowledges and
agrees that:

 

(i)   the
purchaser or holder or its fiduciary has made and shall make all investment decisions for the purchaser or holder and the purchaser
or holder has not relied and shall not rely in any way upon us or our affiliates to act as a fiduciary or adviser of the purchaser
or holder with respect to (A) the design and terms of the Buffered PLUS, (B) the purchaser or holder’s investment in the
Buffered PLUS, or (C) the exercise of or failure to exercise any rights we have under or with respect to the Buffered PLUS;

 

(ii)  we
and our affiliates have acted and will act solely for our own account in connection with (A) all transactions relating to the Buffered
PLUS and (B) all hedging transactions in connection with our obligations under the Buffered PLUS;

 

(iii)  any
and all assets and positions relating to hedging transactions by us or our affiliates are assets and positions of those entities
and are not assets and positions held for the benefit of the purchaser or holder;

 

(iv)  our
interests are adverse to the interests of the purchaser or holder; and

 

(v)   neither
we nor any of our affiliates is a fiduciary or adviser of the purchaser or holder in connection with any such assets, positions
or transactions, and any information that we or any of our affiliates may provide is not intended to be impartial investment advice.

 

Each purchaser and holder of the Buffered PLUS has exclusive
responsibility for ensuring that its purchase, holding and disposition of the Buffered PLUS do not violate the prohibited transaction
rules of ERISA or the Code or any Similar Law. The sale of any Buffered PLUS to any Plan or plan subject to Similar Law is in no
respect a representation by us or any of our affiliates or representatives that such an investment meets all relevant legal requirements
with respect to investments by plans generally or any particular plan, or that such an investment is appropriate for plans generally
or any particular plan. In this regard, neither this discussion nor anything provided in this document is or is intended to be
investment advice directed at any potential Plan purchaser or at Plan purchasers generally and such purchasers of the Buffered
PLUS should consult and rely on their own counsel and advisers as to whether an investment in the Buffered PLUS is appropriate.

 

However, individual retirement accounts, individual retirement
annuities and Keogh plans, as well as

 

Morgan Stanley Finance LLC

Buffered PLUS Based on the iShares® Silver Trust due October 5, 2023 

Buffered Performance Leveraged Upside SecuritiesSM

Principal at Risk Securities

  employee benefit plans that permit participants to direct the investment of their accounts, will not be permitted to purchase or hold the Buffered PLUS if the account, plan or annuity is for the benefit of an employee of Morgan Stanley or Morgan Stanley Wealth Management or a family member and the employee receives any compensation (such as, for example, an addition to bonus) based on the purchase of the Buffered PLUS by the account, plan or annuity.
Additional considerations: Client accounts over which Morgan Stanley, Morgan Stanley Wealth Management or any of their respective subsidiaries have investment discretion are not permitted to purchase the Buffered PLUS, either directly or indirectly.
Supplemental information
regarding plan of distribution; conflicts of interest:

The agent may distribute the Buffered PLUS through Morgan Stanley
Smith Barney LLC (“Morgan Stanley Wealth Management”), as selected dealer, or other dealers, which may include Morgan
Stanley & Co. International plc (“MSIP”) and Bank Morgan Stanley AG. Morgan Stanley Wealth Management, MSIP and
Bank Morgan Stanley AG are affiliates of ours. Selected dealers, including Morgan Stanley Wealth Management, and their financial
advisors will collectively receive from the agent, Morgan Stanley & Co. LLC, a fixed sales commission of $0.25 for each Buffered
PLUS they sell. In addition, Morgan Stanley Wealth Management will receive a structuring fee of $0.05 for each Buffered PLUS.

 

MS & Co. is an affiliate of MSFL and a wholly owned subsidiary
of Morgan Stanley, and it and other affiliates of ours expect to make a profit by selling, structuring and, when applicable, hedging
the Buffered PLUS. When MS & Co. prices this offering of Buffered PLUS, it will determine the economic terms of the Buffered
PLUS such that for each Buffered PLUS the estimated value on the pricing date will be no lower than the minimum level described
in “Investment Summary” on page 2.

 

MS & Co. will conduct this offering in compliance with the
requirements of FINRA Rule 5121 of the Financial Industry Regulatory Authority, Inc., which is commonly referred to as FINRA, regarding
a FINRA member firm’s distribution of the securities of an affiliate and related conflicts of interest. MS & Co. or any
of our other affiliates may not make sales in this offering to any discretionary account. See “Plan of Distribution (Conflicts
of Interest)” and “Use of Proceeds and Hedging” in the accompanying prospectus supplement for PLUS.

Where
you can find more information:

Morgan Stanley and MSFL have filed a registration statement (including
a prospectus, as supplemented by the prospectus supplement for PLUS) with the Securities and Exchange Commission, or SEC, for the
offering to which this communication relates. You should read the prospectus in that registration statement, the prospectus supplement
for PLUS and any other documents relating to this offering that Morgan Stanley and MSFL have filed with the SEC for more complete
information about Morgan Stanley, MSFL and this offering. You may get these documents without cost by visiting EDGAR on the SEC
web site at.www.sec.gov. Alternatively, Morgan Stanley, MSFL, any underwriter or any dealer participating
in the offering will arrange to send you the prospectus supplement for PLUS and prospectus if you so request by calling toll-free
800-584-6837.

 

You may access these documents on the SEC web site at.www.sec.gov.as
follows:

 

Prospectus Supplement for PLUS dated November 16, 2017

 

Prospectus dated November 16, 2017

 

Terms used but not defined in this document are defined in the
prospectus supplement for PLUS or in the prospectus.

 

“Performance Leveraged Upside SecuritiesSM
and “PLUSSM” are our service marks.

 

 

 

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